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Rat Lrr1 cDNA Clone(NM_001109483.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009018

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Gene Information

Cat. No. CDFR009018
Description NativeORF clone of Rattus norvegicus peptidylprolyl isomerase (cyclophilin) like 5 (Ppil5) as transfection-ready DNA NM_001109483.1
Product Type cDAN Clone
Gene Abbr Lrr1
Species Rat
Vector pCMV6Entry
Target Gene LRR1
Background The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
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