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Human LRR1 cDNA Clone(NM_203467.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG013561

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Product Information

Gene Information

Cat. No. CDFG013561
Product Type cDNA clone
Gene Abbr LRR1
Species Human
Size 10 ug
Vector pCMV6-XL
Target Gene LRR1
Background The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Feb 2011]
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