Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR013460
| Cat. No. | CDFR013460 |
| Description | NativeORF clone of Rattus norvegicus lectin, mannose-binding, 1 (Lman1) as transfection-ready DNA NM_053886.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Lman1 |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | LMAN1 |
| Background | The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015] |
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