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Rat Lman1 cDNA Clone(NM_053886.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR013460

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Gene Information

Cat. No. CDFR013460
Description NativeORF clone of Rattus norvegicus lectin, mannose-binding, 1 (Lman1) as transfection-ready DNA NM_053886.1
Product Type cDAN Clone
Gene Abbr Lman1
Species Rat
Vector pCMV6Entry
Target Gene LMAN1
Background The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015]
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