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Mouse Lman1 cDNA Clone(NM_001172062.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG020870

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Gene Information

Cat. No. CDFG020870
Product Type cDNA clone
Gene Abbr Lman1
Species Mouse
ORF Size 1554bp
Size 10 ug
Vector pCMV6Entry
Target Gene LMAN1
Background The protein encoded by this gene is a membrane mannose-specific lectin that cycles between the endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment, and cis-Golgi, functioning as a cargo receptor for glycoprotein transport. The protein has an N-terminal signal sequence, a calcium-dependent and pH-sensitive carbohydrate recognition domain, a stalk region that functions in oligomerization, a transmembrane domain, and a short cytoplasmic domain required for organelle targeting. Allelic variants of this gene are associated with the autosomal recessive disorder combined factor V-factor VIII deficiency. [provided by RefSeq, Jul 2015]
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