Rat Krt81 cDNA Clone(NM_001008814.1)

Name: Rat Krt81 cDNA Clone(NM_001008814.1)
SKU: CDFR001905
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR001905

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Product Information

Gene Information

Cat. No.	CDFR001905
Description	NativeORF clone of Rattus norvegicus type II keratin Kb21 (Kb21) as transfection-ready DNA NM_001008814.1
Product Type	cDAN Clone
Gene Abbr	Krt81
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

KRT81

Background

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. Some human genome assemblies (example T2T-CHM13) have a non-coding version of the gene due to the presence of a SNP that introduces a premature stop codon after codon 281. [provided by RefSeq, Jan 2024]

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