Mouse Krt81 cDNA Clone(NM_001166157.1)

Name: Mouse Krt81 cDNA Clone(NM_001166157.1)
SKU: CDFG020796
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFG020796

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Product Information

Gene Information

Cat. No.	CDFG020796
Product Type	cDNA clone
Gene Abbr	Krt81
Species	Mouse
ORF Size	1446bp
Size	10 ug
Vector	pCMV6Entry

Target Gene

KRT81

Background

The protein encoded by this gene is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this hair keratin, as well as KRTHB3 and KRTHB6, is found primarily in the hair cortex. Mutations in this gene and KRTHB6 have been observed in patients with a rare dominant hair disease, monilethrix. Some human genome assemblies (example T2T-CHM13) have a non-coding version of the gene due to the presence of a SNP that introduces a premature stop codon after codon 281. [provided by RefSeq, Jan 2024]

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