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Rat Kras ORF Clone(NM_031515.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR379710

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Product Information

Gene Information

Cat. No. CDCR379710
Product Type ORF Clone
Gene Abbr Kras
Species Rat
Tag C-terminal Myc-DDK
ORF Size 567 bp
Vector pCMV6-Entry
Target Gene KRAS
Background This gene, a Kirsten ras oncogene homolog from the mammalian ras gene family, encodes a protein that is a member of the small GTPase superfamily. A single amino acid substitution is responsible for an activating mutation. The transforming protein that results is implicated in various malignancies, including lung adenocarcinoma, mucinous adenoma, ductal carcinoma of the pancreas and colorectal carcinoma. Alternative splicing leads to variants encoding two isoforms that differ in the C-terminal region. [provided by RefSeq, Jul 2008]
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