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Rat Kcnj1 cDNA Clone(NM_017023.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011093

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Gene Information

Cat. No. CDFR011093
Description NativeORF clone of Rattus norvegicus potassium inwardly-rectifying channel, subfamily J, member 1 (Kcnj1) as transfection-ready DNA NM_017023.1
Product Type cDAN Clone
Gene Abbr Kcnj1
Species Rat
Vector pCMV6Entry
Target Gene KCNJ1
Background Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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