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Rat Kcna4 cDNA Clone(NM_012971.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR010779

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Gene Information

Cat. No. CDFR010779
Description NativeORF clone of Rattus norvegicus potassium voltage-gated channel, shaker-related subfamily, member 4 (Kcna4) as transfection-ready DNA NM_012971.2
Product Type cDAN Clone
Gene Abbr Kcna4
Species Rat
Vector pCMV6Entry
Target Gene KCNA4
Background Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the A-type potassium current class, the members of which may be important in the regulation of the fast repolarizing phase of action potentials in heart and thus may influence the duration of cardiac action potential.[provided by RefSeq, Mar 2011]
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