Rat Jam3 ORF Clone(NM_001004269.1)

Name: Rat Jam3 ORF Clone(NM_001004269.1)
SKU: CDCR368337
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCR368337

Inquire for Price

Product Information

Gene Information

Cat. No.	CDCR368337
Product Type	ORF Clone
Gene Abbr	Jam3
Species	Rat
Tag	C-terminal Myc-DDK
ORF Size	933 bp
Vector	pCMV6-Entry

Target Gene

JAM3

Background

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. Unlike other proteins in this family, the this protein is unable to adhere to leukocyte cell lines and only forms weak homotypic interactions. The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family. A mutation in an intron of this gene is associated with hemorrhagic destruction of the brain, subependymal calcification, and congenital cataracts. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Apr 2011]

Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Question *

Name

Country *

Email *

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Product Name *

Catalog Name *

Rating

Needs improvement

Satisfaction

General satisfaction

Very satisfaction

Product Review Title *

Summary *