Panoply™ Human JAM3 Knockdown Stable Cell Line

Name: Panoply™ Human JAM3 Knockdown Stable Cell Line
SKU: CSC-DC007856
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC007856

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC007856
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	JAM3
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	JAM3 junctional adhesion molecule 3 [ Homo sapiens ]
Gene Symbol	JAM3
Synonyms	JAMC; JAM-2; JAM-3; JAM-C
Gene ID	83700
Uni Prot ID	Q9BX67
m RNA Refseq	NM_001205329.1
Protein Refseq	NP_001192258.1
Chromosome Location	11q25
Function	integrin binding; protein binding; protein heterodimerization activity; protein homodimerization activity;
Pathway	Cell adhesion molecules (CAMs), organism-specific biosystem; Cell adhesion molecules (CAMs), conserved biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, organism-specific biosystem; Epithelial cell signaling in Helicobacter pylori infection, conserved biosystem; Hemostasis, organism-specific biosystem; Integrin cell surface interactions, organism-specific biosystem;
MIM	606871

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