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Rat Itga5 ORF Clone(NM_001108118.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR374679

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Gene Information

Cat. No. CDCR374679
Product Type ORF Clone
Gene Abbr Itga5
Species Rat
Tag C-terminal Myc-DDK
ORF Size 3300 bp
Vector pCMV6-Entry
Target Gene ITGA5
Background The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
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