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Rat Irf3 cDNA Clone(NM_001006969.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR001499

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Gene Information

Cat. No. CDFR001499
Description NativeORF clone of Rattus norvegicus interferon regulatory factor 3 (Irf3) as transfection-ready DNA NM_001006969.1
Product Type cDAN Clone
Gene Abbr Irf3
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene IRF3
Background This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020]
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