Mouse IRF3 ORF clone (NM_001197127.1)

Name: Mouse IRF3 ORF clone (NM_001197127.1)
SKU: CDCL121593
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL121593

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Product Information

Gene Information

Cat. No.	CDCL121593
Description	Homo sapiens interferon regulatory factor 3 (IRF3), transcript variant 7, mRNA.
Product Type	ORF clone
Gene Abbr	IRF3
Species	Human
ORF Size	465bp
Format	purified plasmid
Vector	pDONR
Warning	Please note that the protein for this clone has been annotated or predicted in the UNIPROT database to have a signal peptide. Placing a tag at the N-terminus of this protein may result in loss of the signal peptide function.

Target Gene

IRF3

Background

This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. The protein plays an important role in the innate immune response against DNA and RNA viruses. Mutations in this gene are associated with Encephalopathy, acute, infection-induced, herpes-specific, 7. [provided by RefSeq, Sep 2020]

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