Rat Il6st cDNA Clone(NM_001008725.3)

Name: Rat Il6st cDNA Clone(NM_001008725.3)
SKU: CDFR001884
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR001884

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Product Information

Gene Information

Cat. No.	CDFR001884
Description	NativeORF clone of Rattus norvegicus interleukin 6 signal transducer (Il6st) as transfection-ready DNA NM_001008725.3
Product Type	cDAN Clone
Gene Abbr	Il6st
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

IL6ST

Background

The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, May 2014]

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