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Rat Il6r cDNA Clone(NM_017020.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011090

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Gene Information

Cat. No. CDFR011090
Description NativeORF clone of Rattus norvegicus interleukin 6 receptor, alpha (Il6ra) as transfection-ready DNA NM_017020.3
Product Type cDAN Clone
Gene Abbr Il6r
Species Rat
Vector pCMV6Entry
Target Gene IL6R
Background This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020]
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