Rat Il1rapl1 cDNA Clone(NM_177935.2)

Name: Rat Il1rapl1 cDNA Clone(NM_177935.2)
SKU: CDFR014905
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR014905

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Product Information

Gene Information

Cat. No.	CDFR014905
Description	NativeORF clone of Rattus norvegicus interleukin 1 receptor accessory protein-like 1 (Il1rapl1) as transfection-ready DNA NM_177935.2
Product Type	cDAN Clone
Gene Abbr	Il1rapl1
Species	Rat
Vector	pCMV6Entry

Target Gene

IL1RAPL1

Background

The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017]

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