Mouse Il1rapl1 cDNA Clone(NM_001160403.1)

Name: Mouse Il1rapl1 cDNA Clone(NM_001160403.1)
SKU: CDFG020019
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFG020019

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Product Information

Gene Information

Cat. No.	CDFG020019
Product Type	cDNA clone
Gene Abbr	Il1rapl1
Species	Mouse
ORF Size	2091bp
Size	10 ug
Vector	pCMV6Entry

Target Gene

IL1RAPL1

Background

The protein encoded by this gene is a member of the interleukin 1 receptor family and is similar to the interleukin 1 accessory proteins. This protein has an N-terminal signal peptide, three extracellular immunoglobulin Ig-like domains, a transmembrane domain, an intracellular Toll/IL-1R domain, and a long C-terminal tail which interacts with multiple signalling molecules. This gene is located at a region on chromosome X that is associated with a non-syndromic form of X-linked intellectual disability. Deletions and mutations in this gene were found in patients with intellectual disability. This gene is expressed at a high level in post-natal brain structures involved in the hippocampal memory system, which suggests a specialized role in the physiological processes underlying memory and learning abilities, and plays a role in synapse formation and stabilization. [provided by RefSeq, Jul 2017]

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