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Rat Il17ra cDNA Clone(NM_001107883.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR007530

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Gene Information

Cat. No. CDFR007530
Description NativeORF clone of Rattus norvegicus interleukin 17 receptor A (Il17ra) as transfection-ready DNA NM_001107883.2
Product Type cDAN Clone
Gene Abbr Il17ra
Species Rat
Vector pCMV6Entry
Target Gene IL17RA
Background Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]
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