Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR007530
| Cat. No. | CDFR007530 |
| Description | NativeORF clone of Rattus norvegicus interleukin 17 receptor A (Il17ra) as transfection-ready DNA NM_001107883.2 |
| Product Type | cDAN Clone |
| Gene Abbr | Il17ra |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | IL17RA |
| Background | Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014] |
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