Mouse IL17RA ORF clone(NM_008359.2)

Name: Mouse IL17RA ORF clone(NM_008359.2)
SKU: CDCL184778
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDCL184778

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Product Information

Gene Information

Cat. No.	CDCL184778
Description	ORF Clone of Mus musculus interleukin 17 receptor A DNA.
Product Type	ORF clone
Gene Abbr	IL17RA
Species	Mouse
ORF Size	2595bp
Vector	pMD18-T
Warning	This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Storage	store at -20°C

Target Gene

IL17RA

Background

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. The transmembrane protein encoded by this gene (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2014]

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