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Rat Igfbp7 cDNA Clone(NM_001013048.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR002776

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Gene Information

Cat. No. CDFR002776
Description NativeORF clone of Rattus norvegicus insulin-like growth factor binding protein 7 (Igfbp7) as transfection-ready DNA NM_001013048.1
Product Type cDAN Clone
Gene Abbr Igfbp7
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene IGFBP7
Background This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
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