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Mouse Igfbp7 cDNA Clone(NM_001159518.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019874

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Gene Information

Cat. No. CDFG019874
Product Type cDNA clone
Gene Abbr Igfbp7
Species Mouse
ORF Size 942bp
Size 10 ug
Vector pCMV6Entry
Target Gene IGFBP7
Background This gene encodes a member of the insulin-like growth factor (IGF)-binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF-I and IGF-II with relatively low affinity, and belongs to a subfamily of low-affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants encoding different isoforms have been described for this gene, and one variant has been associated with retinal arterial macroaneurysm (PMID:21835307). [provided by RefSeq, Dec 2011]
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