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Rat Htr2b ORF Clone(NM_017250.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378314

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Product Information

Gene Information

Cat. No. CDCR378314
Product Type ORF Clone
Gene Abbr Htr2b
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1440 bp
Vector pCMV6-Entry
Target Gene HTR2B
Background This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016]
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