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Rat Hs2st1 cDNA Clone(NM_001100518.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR005081

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Gene Information

Cat. No. CDFR005081
Description NativeORF clone of Rattus norvegicus heparan sulfate 2-O-sulfotransferase 1 (Hs2st1) as transfection-ready DNA NM_001100518.1
Product Type cDAN Clone
Gene Abbr Hs2st1
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene HS2ST1
Background Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]
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