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Rat Hs2st1 ORF Clone(NM_001100518.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR372302

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Gene Information

Cat. No. CDCR372302
Product Type ORF Clone
Gene Abbr Hs2st1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 1071 bp
Vector pCMV6-Entry
Target Gene HS2ST1
Background Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. This gene encodes a member of the heparan sulfate biosynthetic enzyme family that transfers sulfate to the 2 position of the iduronic acid residue of heparan sulfate. The disruption of this gene resulted in no kidney formation in knockout embryonic mice, indicating that the absence of this enzyme may interfere with the signaling required for kidney formation. Two alternatively spliced transcript variants that encode different proteins have been found for this gene. [provided by RefSeq, Aug 2008]
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