Rat Gjb2 cDNA Clone(NM_001004099.1)

Name: Rat Gjb2 cDNA Clone(NM_001004099.1)
SKU: CDFR001300
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR001300

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Product Information

Gene Information

Cat. No.	CDFR001300
Description	NativeORF clone of Rattus norvegicus gap junction protein, beta 2 (Gjb2) as transfection-ready DNA NM_001004099.1
Product Type	cDAN Clone
Gene Abbr	Gjb2
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

GJB2

Background

This gene encodes a member of the gap junction protein family. The gap junctions were first characterized by electron microscopy as regionally specialized structures on plasma membranes of contacting adherent cells. These structures were shown to consist of cell-to-cell channels that facilitate the transfer of ions and small molecules between cells. The gap junction proteins, also known as connexins, purified from fractions of enriched gap junctions from different tissues differ. According to sequence similarities at the nucleotide and amino acid levels, the gap junction proteins are divided into two categories, alpha and beta. Mutations in this gene are responsible for as much as 50% of pre-lingual, recessive deafness. [provided by RefSeq, Oct 2008]

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