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Human GJB2 adenoviral particles

For research use only. Not intended for any clinical use.

Cat. No. :   AD06777Z

Storage :   -80℃ Shipping :   Frozen on dry ice

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Virus Particles Information

Quality Control

Gene Information

Cat. No. AD06777Z
Description Adenovirus with ORF of gap junction protein, beta 2, 26kDa (GJB2).
Gene GJB2
Species Human
Titer Varies lot by lot, for example, ≥1x10^10 IFU/mL, ≥1x10^11 IFU/mL, ≥1x10^11 VP/mL etc.
Size Varies lot by lot, for example, 100 ul, 500 ul, 1 mL etc.
Storage Store at -80℃. Avoid multiple freeze/thaw cycles.
Shipping Frozen on dry ice
Summary Creative Biogene ensures high-quality adenovirus particles by optimizing and standardizing production protocols and performing stringent quality control (QC). The specific QC experiments performed vary between adenovirus particle lots.
Endotoxin Endotoxins, primarily derived from Gram-negative bacteria, can trigger adverse immune responses. Endotoxin contamination is a significant concern in adenovirus production, especially for applications in animal studies and gene therapy. Creative Biogene utilizes rigorous endotoxin detection methods to monitor the endotoxin level in our produced adenovirus particles to ensure regulatory compliance.
Sterility Creative Biogene ensures that adenovirus products are free of any bacterial, fungal and other microbial contamination.
Ad5 E1 Detection All Creative Biogene adenoviruses are PCR tested to ensure that there are no detectable E1 sequences in the particles, which could be from revertants or external E1 contamination.
RCA Assays Adenovirus products originating at Creative Biogene are guaranteed to have undetectable replication-competent adenovirus (RCA). This quality control measure is important because there is always the possibility of wild-type contamination due to revertants or environmental sources.
PFU Titering All purified adenovirus preparations are tested for infectious titer. Creative Biogene's PFU test takes a few days longer but counts true plaques in HEK cells rather than estimating PFU titers via IHC staining or TCI50 of infected cells.
Gene Name GJB2 gap junction protein, beta 2, 26kDa [ Homo sapiens ]
Gene Symbol GJB2
Synonyms GJB2; gap junction protein, beta 2, 26kDa; DFNA3, DFNB1, gap junction protein, beta 2, 26kD (connexin 26) , gap junction protein, beta 2, 26kDa (connexin 26); gap junction beta-2 protein; connexin 26; CX26; NSRD1; HID; KID; PPK; DFNA3; DFNB1; DFNA3A; DFNB1A;
Gene ID 2706
Uni Prot ID P29033
m RNA Refseq BC017048
Chromosome Location 13q11-q12
Function gap junction channel activity;
Pathway Calcium Regulation in the Cardiac Cell, organism-specific biosystem; Gap junction assembly, organism-specific biosystem; Gap junction trafficking, organism-specific biosystem; Gap junction trafficking and regulation, organism-specific biosystem; Membrane Trafficking, organism-specific biosystem; Oligomerization of connexins into connexons, organism-specific biosystem; Transport of connexins along the secretory pathway, organism-specific biosystem;
MIM 121011
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