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Rat Fgf2 ORF Clone(NM_019305.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR378599

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Gene Information

Cat. No. CDCR378599
Product Type ORF Clone
Gene Abbr Fgf2
Species Rat
Tag C-terminal Myc-DDK
ORF Size 465 bp
Vector pCMV6-Entry
Target Gene FGF2
Background The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. This protein has been implicated in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. The mRNA for this gene contains multiple polyadenylation sites, and is alternatively translated from non-AUG (CUG) and AUG initiation codons, resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF. [provided by RefSeq, Jul 2008]
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