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Rat F5 ORF Clone(NM_001047878.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR371961

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Product Information

Gene Information

Cat. No. CDCR371961
Product Type ORF Clone
Gene Abbr F5
Species Rat
Tag C-terminal Myc-DDK
ORF Size 6309 bp
Vector pCMV6-Entry
Target Gene F5
Background This gene encodes an essential cofactor of the blood coagulation cascade. This factor circulates in plasma, and is converted to the active form by the release of the activation peptide by thrombin during coagulation. This generates a heavy chain and a light chain which are held together by calcium ions. The activated protein is a cofactor that participates with activated coagulation factor X to activate prothrombin to thrombin. Defects in this gene result in either an autosomal recessive hemorrhagic diathesis or an autosomal dominant form of thrombophilia, which is known as activated protein C resistance. [provided by RefSeq, Oct 2008]
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