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Rat Dlc1 cDNA Clone(NM_001127446.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR009537

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Gene Information

Cat. No. CDFR009537
Description NativeORF clone of Rattus norvegicus deleted in liver cancer 1 (Dlc1) as transfection-ready DNA NM_001127446.1
Product Type cDAN Clone
Gene Abbr Dlc1
Species Rat
Vector pCMV6Entry
Target Gene DLC1
Background This gene encodes a GTPase-activating protein (GAP) that is a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins. GAP family proteins participate in signaling pathways that regulate cell processes involved in cytoskeletal changes. This gene functions as a tumor suppressor gene in a number of common cancers, including prostate, lung, colorectal, and breast cancers. Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene.[provided by RefSeq, Apr 2010]
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