Panoply™ Human DLC1 Knockdown Stable Cell Line

Name: Panoply™ Human DLC1 Knockdown Stable Cell Line
SKU: CSC-DC004333
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC004333

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC004333
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	DLC1
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	DLC1 deleted in liver cancer 1 [ Homo sapiens ]
Gene Symbol	DLC1
Synonyms	DLC1; deleted in liver cancer 1; rho GTPase-activating protein 7; ARHGAP7; DLC 1; HP; p122 RhoGAP; StAR related lipid transfer (START) domain containing 12; STARD12; Rho-GTPase-activating protein 7; deleted in liver cancer 1 protein; START domain-containing protein 12; deleted in liver cancer 1 variant 2; rho-type GTPase-activating protein 7; StAR-related lipid transfer (START) domain containing 12; p122-RhoGAP; FLJ21120;
Gene ID	10395
Uni Prot ID	Q96QB1
m RNA Refseq	BC049842
Chromosome Location	8p22
Function	GTPase activator activity; NOT Rac GTPase activator activity; Rho GTPase activator activity; Rho GTPase activator activity; SH2 domain binding; phospholipase binding; protein binding; vinculin binding;
Pathway	Regulation of RhoA activity, organism-specific biosystem; Rho GTPase cycle, organism-specific biosystem; Signal Transduction, organism-specific biosystem; Signaling by Rho GTPases, organism-specific biosystem;
MIM	604258

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