Transfected Stable Cell Lines
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Cat. No. : CDCR375311
| Cat. No. | CDCR375311 |
| Product Type | ORF Clone |
| Gene Abbr | Dctn3 |
| Species | Rat |
| Tag | C-terminal Myc-DDK |
| ORF Size | 561 bp |
| Vector | pCMV6-Entry |
| Target Gene | DCTN3 |
| Background | This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013] |
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