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Rat Dctn3 ORF Clone(NM_001108659.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR375311

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Product Information

Gene Information

Cat. No. CDCR375311
Product Type ORF Clone
Gene Abbr Dctn3
Species Rat
Tag C-terminal Myc-DDK
ORF Size 561 bp
Vector pCMV6-Entry
Target Gene DCTN3
Background This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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