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Mouse Dctn3 cDNA Clone(NM_001159565.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFG019898

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Product Information

Gene Information

Cat. No. CDFG019898
Product Type cDNA clone
Gene Abbr Dctn3
Species Mouse
ORF Size 480bp
Size 10 ug
Vector pCMV6Entry
Target Gene DCTN3
Background This gene encodes the smallest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, cytokinesis, chromosome movement, nuclear positioning, and axonogenesis. This subunit, like most other dynactin subunits, exists only as a part of the dynactin complex. It is primarily an alpha-helical protein with very little coiled coil, and binds directly to the largest subunit (p150) of dynactin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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