Transfected Stable Cell Lines
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Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR012260
| Cat. No. | CDFR012260 |
| Description | NativeORF clone of Rattus norvegicus decorin (Dcn) as transfection-ready DNA NM_024129.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Dcn |
| Species | Rat |
| Vector | pCMV6Entry |
| Target Gene | DCN |
| Background | This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015] |
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