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Rat Dcn cDNA Clone(NM_024129.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012260

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Gene Information

Cat. No. CDFR012260
Description NativeORF clone of Rattus norvegicus decorin (Dcn) as transfection-ready DNA NM_024129.1
Product Type cDAN Clone
Gene Abbr Dcn
Species Rat
Vector pCMV6Entry
Target Gene DCN
Background This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015]
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