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Rat Cyp8b1 cDNA Clone(NM_031241.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012620

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Gene Information

Cat. No. CDFR012620
Description NativeORF clone of Rattus norvegicus cytochrome P450, family 8, subfamily b, polypeptide 1 (Cyp8b1) as transfection-ready DNA NM_031241.1
Product Type cDAN Clone
Gene Abbr Cyp8b1
Species Rat
Vector pCMV6Entry
Target Gene CYP8B1
Background This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the conversion of 7 alpha-hydroxy-4-cholesten-3-one into 7-alpha,12-alpha-dihydroxy-4-cholesten-3-one. The balance between these two steroids determines the relative amounts of cholic acid and chenodeoxycholic acid both of which are secreted in the bile and affect the solubility of cholesterol. This gene is unique among the cytochrome P450 genes in that it is intronless. [provided by RefSeq, Jul 2008]
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