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Panoply™ Human CYP8B1 Knockdown Stable Cell Line

Cat.No.
CSC-DC003990
Description
Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by RT-PCR. Cells are rigorously qualified and mycoplasma free.
Growth Properties
Adherent
Host Cell
HEK293 (Hela and other cell types are also available)
Morphology
Epithelial
Quality Control
Negative for bacteria, yeast, fungi and mycoplasma.
Shipping
Dry Ice
Size/Form
2 × 10^6 cells / vial
Species
Human
Storage
Liquid Nitrogen
Gene Information
Gene Symbol
CYP8B1
Synonyms
CP8B; CYP12
Gene Description
cytochrome P450, family 8, subfamily B, polypeptide 1
Gene ID
UniProt ID
Q9UNU6
mRNA Refseq
Protein Refseq
Chromosome Location
3p22.1
Function
7alpha-hydroxycholest-4-en-3-one 12alpha-hydroxylase activity; electron carrier activity; heme binding; iron ion binding; oxygen binding; sterol 12-alpha-hydroxylase activity;
Pathway
Bile acid and bile salt metabolism, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, organism-specific biosystem; Bile acid biosynthesis, cholesterol => cholate, conserved biosystem; Biological oxidations, organism-specific biosystem; Cytochrome P450 - arranged by substrate type, organism-specific biosystem;
MIM

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