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Rat Cxcr1 cDNA Clone(NM_019310.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR011401

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Gene Information

Cat. No. CDFR011401
Description NativeORF clone of Rattus norvegicus interleukin 8 receptor, alpha (Il8ra) as transfection-ready DNA NM_019310.1
Product Type cDAN Clone
Gene Abbr Cxcr1
Species Rat
Vector pCMV6Entry
Target Gene CXCR1
Background The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008]
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