Pages
Products

Rat Coch cDNA Clone(NM_001108710.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR008298

Inquire for Price

Product Information

Gene Information

Cat. No. CDFR008298
Description NativeORF clone of Rattus norvegicus coagulation factor C homolog, cochlin (Limulus polyphemus) (Coch) as transfection-ready DNA NM_001108710.1
Product Type cDAN Clone
Gene Abbr Coch
Species Rat
Vector pCMV6Entry
Target Gene COCH
Background The protein encoded by this gene is highly conserved in human, mouse, and chicken, showing 94% and 79% amino acid identity of human to mouse and chicken sequences, respectively. Hybridization to this gene was detected in spindle-shaped cells located along nerve fibers between the auditory ganglion and sensory epithelium. These cells accompany neurites at the habenula perforata, the opening through which neurites extend to innervate hair cells. This and the pattern of expression of this gene in chicken inner ear paralleled the histologic findings of acidophilic deposits, consistent with mucopolysaccharide ground substance, in temporal bones from DFNA9 (autosomal dominant nonsyndromic sensorineural deafness 9) patients. Mutations that cause DFNA9 have been reported in this gene. Alternative splicing results in multiple transcript variants encoding the same protein. Additional splice variants encoding distinct isoforms have been described but their biological validities have not been demonstrated. [provided by RefSeq, Oct 2008]
Quick Inquiry

Q & A

Customer Reviews

Ask a Question

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

Write a Review

Write a review of your use of Biogene products and services in your research. Your review can help your fellow researchers make informed purchasing decisions.

Needs improvement

Satisfaction

General satisfaction

Very satisfaction