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Rat Cldn3 cDNA Clone(NM_031700.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR012836

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Gene Information

Cat. No. CDFR012836
Description NativeORF clone of Rattus norvegicus claudin 3 (Cldn3) as transfection-ready DNA NM_031700.2
Product Type cDAN Clone
Gene Abbr Cldn3
Species Rat
Target Gene CLDN3
Background Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this intronless gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is also a low-affinity receptor for Clostridium perfringens enterotoxin, and shares aa sequence similarity with a putative apoptosis-related protein found in rat. [provided by RefSeq, Jul 2008]
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