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Rat Cdkn1c cDNA Clone(NM_182735.2)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR015023

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Gene Information

Cat. No. CDFR015023
Description NativeORF clone of Rattus norvegicus cyclin-dependent kinase inhibitor 1C (P57) (Cdkn1c), transcript variant 3 as transfection-ready DNA NM_182735.2
Product Type cDAN Clone
Gene Abbr Cdkn1c
Species Rat
Vector pCMV6Entry
Target Gene CDKN1C
Background This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
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