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Rat Cdkn1c cDNA Clone(NM_001033757.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR004272

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Gene Information

Cat. No. CDFR004272
Description NativeORF clone of Rattus norvegicus cyclin-dependent kinase inhibitor 1C (P57) (Cdkn1c), transcript variant 1 as transfection-ready DNA NM_001033757.1
Product Type cDAN Clone
Gene Abbr Cdkn1c
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene CDKN1C
Background This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
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