Rat Camkk2 cDNA Clone(NM_031338.1)

Name: Rat Camkk2 cDNA Clone(NM_031338.1)
SKU: CDFR012643
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR012643

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Product Information

Gene Information

Cat. No.	CDFR012643
Description	NativeORF clone of Rattus norvegicus calcium/calmodulin-dependent protein kinase kinase 2, beta (Camkk2) as transfection-ready DNA NM_031338.1
Product Type	cDAN Clone
Gene Abbr	Camkk2
Species	Rat
Vector	pCMV6Entry

Target Gene

CAMKK2

Background

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]

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