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Mouse CAMKK2 ORF clone(NM_001199676.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCG012655

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Product Information

Gene Information

Cat. No. CDCG012655
Product Type ORF clone
Gene Abbr CAMKK2
Species Mouse
Host Cell Bacterial
Source Bacteria
ORF Size 4903bp
Size 1ug
Format Clear Liquid
Vector pORF
Buffer 10mM Tris-HCI, 1mM EDTA, pH8.0
Warning pORF-mCamkk2 ORF Vector is for research use only and is not intended for therapeutic or diagnostic applications. Please contact a technical service representative for more information.
Storage 1 year when stored at -20°C or lower in a non-frost free freezer.
Target Gene CAMKK2
Background The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. The major isoform of this gene plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Protein products of this gene also phosphorylate AMP-activated protein kinase (AMPK). This gene has its strongest expression in the brain and influences signalling cascades involved with learning and memory, neuronal differentiation and migration, neurite outgrowth, and synapse formation. Alternative splicing results in multiple transcript variants encoding distinct isoforms. The identified isoforms differ in their ability to undergo autophosphorylation and to phosphorylate downstream kinases. [provided by RefSeq, Jul 2012]
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