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Rat Bub1 ORF Clone(NM_001106507.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDCR373292

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Product Information

Gene Information

Cat. No. CDCR373292
Product Type ORF Clone
Gene Abbr Bub1
Species Rat
Tag C-terminal Myc-DDK
ORF Size 3180 bp
Vector pCMV6-Entry
Target Gene BUB1
Background This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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