Rat Atad3a cDNA Clone(NM_001034922.1)

Name: Rat Atad3a cDNA Clone(NM_001034922.1)
SKU: CDFR004407
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR004407

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Product Information

Gene Information

Cat. No.	CDFR004407
Description	NativeORF clone of Rattus norvegicus ATPase family, AAA domain containing 3A (Atad3a) as transfection-ready DNA NM_001034922.1
Product Type	cDAN Clone
Gene Abbr	Atad3a
Species	Rat
Size	10 ug
Vector	pCMV6Entry

Target Gene

ATAD3A

Background

This gene encodes a ubiquitously expressed mitochondrial membrane protein that contributes to mitochondrial dynamics, nucleoid organization, protein translation, cell growth, and cholesterol metabolism. This gene is a member of the ATPase family AAA-domain containing 3 gene family which, in humans, includes two other paralogs. Naturally occurring mutations in this gene are associated with distinct neurological syndromes including Harel-Yoon syndrome. High-level expression of this gene is associated with poor survival in breast cancer patients. A homozygous knockout of the orthologous gene in mice results in embryonic lethality at day 7.5 due to growth retardation and defective development of the trophoblast lineage. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

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