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Rat Arap2 cDNA Clone(NM_001107216.1)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFR006941

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Gene Information

Cat. No. CDFR006941
Description NativeORF clone of Rattus norvegicus ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2 (Arap2) as transfection-ready DNA NM_001107216.1
Product Type cDAN Clone
Gene Abbr Arap2
Species Rat
Size 10 ug
Vector pCMV6Entry
Target Gene ARAP2
Background The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
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