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Mouse Arap2 cDNA Clone(NM_178407.3)

For research use only. Not intended for any clinical use.

Cat. No. :   CDFL001367

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Gene Information

Cat. No. CDFL001367
Product Type cDNA clone
Gene Abbr Arap2
Species Mouse
Size 10 ug
Vector pCMV6Entry
Target Gene ARAP2
Background The protein encoded by this gene contains ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology domains. The protein is a phosphatidylinositol (3,4,5)-trisphosphate-dependent Arf6 GAP that binds RhoA-GTP, but it lacks the predicted catalytic arginine in the RHO-GAP domain and does not have RHO-GAP activity. The protein associates with focal adhesions and functions downstream of RhoA to regulate focal adhesion dynamics. [provided by RefSeq, Sep 2008]
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