Rat Alg11 cDNA Clone(NM_001108401.1)

Name: Rat Alg11 cDNA Clone(NM_001108401.1)
SKU: CDFR008020
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CDFR008020

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Product Information

Gene Information

Cat. No.	CDFR008020
Description	NativeORF clone of Rattus norvegicus asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) (Alg11) as transfection-ready DNA NM_001108401.1
Product Type	cDAN Clone
Gene Abbr	Alg11
Species	Rat
Vector	pCMV6Entry

Target Gene

ALG11

Background

This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19. [provided by RefSeq, Aug 2010]

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