Panoply™ Human ALG11 Knockdown Stable Cell Line

Name: Panoply™ Human ALG11 Knockdown Stable Cell Line
SKU: CSC-DC000498
Availability: InStock

For research use only. Not intended for any clinical use.

Cat. No. : CSC-DC000498

Host Cell : HEK293 (Hela and other cell types are also available) Validation : Real-Time RCR

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Cell Line Information

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Gene Information

Cat. No.	CSC-DC000498
Description	Creative Biogene's Knockdown Cell Lines are target specific shRNA lentivirus transduced cells. The percent knockdown levels range from 75-99% depending on the gene, as evaluated by Real-Time RCR. Cells are rigorously qualified and mycoplasma free.
Target Gene	ALG11
Host Cell	HEK293 (Hela and other cell types are also available)
Host Cell Species	Homo sapiens (Human)
Applications	(1) Studying gene functions (2) Studying gene interactions and signaling pathways (3) Target validation and drug discovery (4) Designing diseases models
Size	>1 × 10⁶ cells / vial
Stability	Validated for at least 10 passages
Validation	Real-Time RCR
Quality Control	Negative for bacteria, yeast, fungi and mycoplasma.
Storage	Liquid Nitrogen
Shipping	Dry Ice

Mycoplasma	Negative
Format	One frozen vial containing millions of cells
Storage	Liquid nitrogen
Safety Considerations	The following safety precautions should be observed. 1. Use pipette aids to prevent ingestion and keep aerosols down to a minimum. 2. No eating, drinking or smoking while handling the stable line. 3. Wash hands after handling the stable line and before leaving the lab. 4. Decontaminate work surface with disinfectant or 70% ethanol before and after working with stable cells. 5. All waste should be considered hazardous. 6. Dispose of all liquid waste after each experiment and treat with bleach.
Ship	Dry ice

Gene Name	ALG11 asparagine-linked glycosylation 11, alpha-1,2-mannosyltransferase homolog (yeast) [ Homo sapiens ]
Gene Symbol	ALG11
Synonyms	GT8; CDG1P
Gene ID	440138
Uni Prot ID	Q2TAA5
m RNA Refseq	NM_001004127.2
Protein Refseq	NP_001004127.2
Chromosome Location	13q14.2
Function	GDP-Man:Man3GlcNAc2-PP-Dol alpha-1,2-mannosyltransferase activity;
Pathway	Asparagine N-linked glycosylation, organism-specific biosystem; Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; N-Glycan biosynthesis, organism-specific biosystem; N-Glycan biosynthesis, conserved biosystem; N-glycan precursor biosynthesis, organism-specific biosystem; N-glycan precursor biosynthesis, conserved biosystem;
MIM	613666

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