Transfected Stable Cell Lines
Reliable | High-Performance | Wide Rage
Precision reporter, kinase, immune receptor, biosimilar, Cas9, and knockout stable cell lines for diverse applications.
Cat. No. : CDFR006117
| Cat. No. | CDFR006117 |
| Description | NativeORF clone of Rattus norvegicus autoimmune regulator (Aire) as transfection-ready DNA NM_001106379.1 |
| Product Type | cDAN Clone |
| Gene Abbr | Aire |
| Species | Rat |
| Size | 10 ug |
| Vector | pCMV6Entry |
| Target Gene | AIRE |
| Background | This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012] |
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